OUR WORK ON THE COVER
Wonderful collaborative work on a Structure Guided Drug Development (SGDD) adventure leading to selective inhibitors against Trypanosma brucei methionyl-tRNA synthetase.
The compounds need further optimization to cross the blood brain barrier (BBB) but are now in the low-nanomolar range after a huge team effort.
I feel honored to have worked with such super talented group of medicinal chemists, parasitologists, computational and structural biologists from @UWMedicine, @UWBiochemistry and @PATHdrugdev.
It is also a pleasure to be on the cover of @rsc_medchem with the fantastic art of Ouliana Panova @panovanator.
