OUR WORK ON THE COVER

Wonderful collaborative work on a Structure Guided Drug Development (SGDD) adventure leading to selective inhibitors against Trypanosma brucei methionyl-tRNA synthetase. 

The compounds need further optimization to cross the blood brain barrier (BBB) but are now in the low-nanomolar range after a huge team effort. 

I feel honored to have worked with such super talented group of medicinal chemists, parasitologists, computational and structural biologists from @UWMedicine@UWBiochemistry and @PATHdrugdev.

It is also a pleasure to be on the cover of @rsc_medchem with the fantastic art of Ouliana Panova @panovanator.

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HOME

OUR WORK ON THE COVER

Wonderful collaborative work on a Structure Guided Drug Development (SGDD) adventure leading to selective inhibitors against Trypanosma brucei methionyl-tRNA synthetase. 

The compounds need further optimization to cross the blood brain barrier (BBB) but are now in the low-nanomolar range after a huge team effort. 

I feel honored to have worked with such super talented group of medicinal chemists, parasitologists, computational and structural biologists from @UWMedicine@UWBiochemistry and @PATHdrugdev.

It is also a pleasure to be on the cover of @rsc_medchem with the fantastic art of Ouliana Panova @panovanator.

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